Yes, simple create a dialing plan in Axon that will use the appropriate line based on the dialed number (eg if number starts with 2, use line 2 and remove the "2" digit from the start of the number, otherwise use line 1).
Then using your softphone or hardware phone / ata adapter's transfer feature (if it has one) to initiate a call transfer and use the dialing rules you have set in Axon to dial the number with the 2nd line (eg 2 NNN NNNN).
If you want an automatic transfer (eg, you call in to your house, and then get a prompt where you are asked to enter the number you wish to dial and then have it transfer you so you don't pay outrageous cellphone prices for the long distance call, then you will need IVM.