In this case, this could be due to network connectivity. It also could be the other side echo-cancellation not working well. Of course the other side of the call could just be noisy.
You may ask the other party to use a handset if they are using hands free. Use a different "Quality / Bandwidth" setting using the Express Talk Settings. Adjustments could be made on either side of the call.
If the other side is not Express Talk (eg. it is an IP-Phone) select a different preferred codec on that other device if it lets you. GSM 6.10 is recommended codec for lower bandwidth scenarios.